Publishing a Microsoft ClickOnce Setup / Deploying ClickOnce using an Apache Webserver
Although it might seem as though you can only use Microsoft’s ClickOnce installers with IIS, this is simply not true, as all you need to do is set some mime types on the server.
The simplest way to do this is to add the following lines to a .htaccess file in the folder containing the ClickOnce files:
AddType application/x-ms-application application
AddType application/x-ms-manifest manifest
AddType application/octet-stream deploy
For some reason I also needed the following line in my .htaccess file
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